A. M. Bezanson (Ancel Maynard) had come to the Peace River Country in 1906. On returning to Edmonton he published a pamphlet, 'The Peace River Trail', in May 1907 in an effort to increase interest in the area. He settled near the junction of the Wapiti, Smoky, and Simonette rivers in 1908 and started a settlement there. Bezanson was established in 1910, when it was expected that the Grande Prairie-Grande Cache Railway would pass through the region. The settlement grew until 1914, when it was found that the railway would pass to the north through Rycroft. The townsite was moved to be near the highway.
The Post office opened on December 17, 1915.